The NGAL test for clinical chemistry analyzers (Bioporto)
The NGAL TestTM for clinical chemistry analyzers (BioPorto)
- Numbers of tests: 92 on Hitachi 917 (Can vary based on analyzer model)
- Assay time: 10 minutes
- Result type: Quantitative
- Regulatory status: For in vitro diagnostic use in the European Union only
INTENDED USE
The NGAL Test™ is a particle-enhanced turbidimetric immunoassay for the quantitative determination of neutrophil gelatinase-associated lipocalin (NGAL) in human urine and EDTA plasma on automated clinical chemistry analyzers. NGAL measurements are useful in the diagnosis of acute kidney injury which may lead to acute renal failure.
NGAL is a novel biomarker for diagnosing acute kidney injury (AKI)
Its key advantage is that it respondsearlier than other renal status markers like serum creatinine and shows a proportionate response to injury. NGAL determination thus permits the early diagnosis and prognostic stratification of patients with AKI.
Clinical application
Measuring NGAL in urine or plasma gives you information on AKI status that you need for rapid decision making e.g. in the following settings:
- Intensive care - monitoring
- Emergency room - triage tool
- Renal transplantation - predictive evaluation
- Intravenous contrast agents - assessing nephrotoxicity
What is NGAL?
NGAL (neutrophil gelatinase-associated lipocalin, lipocalin-2, siderocalin) is a small protein expressed in neutrophils and certain epithelia, including the renal tubules. Renal expression of NGAL is dramatically increased in kidney injury from a variety of causes, and NGAL is released into both urine and plasma. NGAL levels rise within 2 hours of the insult, making NGAL an early and sensitive biomarker of kidney injury.
Assay specifications
- Method: Particle-enhanced turbidimetric immunoassay
- Sample: Urine and EDTA plasma
- Sample stability: If the assay cannot be performed within 24 hours or specimens are to be shipped, freeze the specimens at -20°C or below. For long-term storage of specimens, -70°C or below is recommended.
- Measuring range: 25 to 5,000 ng/mL
- Assay time: 10 minutes (Hitachi 917) (Can vary based on analyzer model)
- Shelf life: 12 month
- Open vial stability: 30 days
- On board stability: 30 days (when refrigerated)
More information
You will find more information about NGAL on www.ngal.cz (in Czech language only)
| Catalog number | Description | Price excl. VAT |
|---|---|---|
| ST001CA | NGAL Test Reagent Kit | 45 000 CZK |
